Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester - Names and Identifiers
Name | Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester
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Synonyms | methyl 3-bromoH-imidazo[1,2-a]pyridine-6-carboxylate 3-Bromoimidazo[1,2-a]pyridine-6-carboxylicacid methyl ester 3-Bromo-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl es... IMidazo[1,2-a]pyridine-6-carboxylic acid, 3-broMo-, Methyl ester
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CAS | 886361-98-4
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EINECS | 604-604-1 |
Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester - Physico-chemical Properties
Molecular Formula | C9H7BrN2O2
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Molar Mass | 255.07 |
Density | 1.68±0.1 g/cm3(Predicted) |
Melting Point | 162~163℃ |
pKa | 2.23±0.50(Predicted) |
Storage Condition | 2-8°C |
Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester - Introduction
Imidazo[1,2-a]pyridine-6-carboxylicacid-, 3-bromo-, methyl ester is an organic compound with the chemical formula C9H6BrN3O2.
Nature:
Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester is a white crystalline solid with strong flammability and is soluble in some organic solvents such as chloroform, dimethyl sulfoxide and ethyl acetate.
Use:
The compound has certain application value in drug synthesis. It can be used as an intermediate in organic synthesis for the synthesis of other compounds. In addition, it can also be used for DNA-TAG labeling and fluorescent probes in chemical research.
Preparation Method:
Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester can be synthesized by the following steps:
1. First, imidazole-2-carboxylic acid and methyl 3-bromopropionate are reacted under alkaline conditions to produce methyl 3-bromoimidazole-2-carboxylate.
2. Then, 3-bromoimidazole-2-carboxylic acid methyl ester and methyl acetate are reacted under alkaline conditions to obtain Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester.
Safety Information:
Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-, methyl ester should avoid contact with fire and high temperature during storage and operation, and should be stored in a cool and dry place. Please wear protective glasses and gloves when using, and maintain good ventilation conditions. At the same time, avoid inhaling its vapor or dust. If exposed, flush immediately with plenty of water and seek medical help.
Last Update:2024-04-09 21:11:58